Pleural mesothelioma is a very rare cancerous lump that grows in the pleura or peritoneum. It begins in the mesothelial cells.
The pleura are a blanket encircles not only the lungs (the bronchi) but also the wall within the rib cage. This tumor particularly attacks men who are over the age of 50.
The symptoms are mainly respiratory; they are attached to the growth of the tumor (which will compress the lungs). The main and the most frequent signs are as follows:
• Chest or back pain
• Cough, shortness of breath.
• Weight loss
• Night sweats
• Lateral chest pain
• Smoking leads to some risks.
Inhalation of asbestos fibers is the main known cause of pleural mesothelioma. We do not forget the natural and industrial fibers such as ceramics, and the simian virus 40. Other genetic causes appear, mainly the loss of BAP1 expression or also the BRCA1-associated protein.
In cancer treatment, different types of physicians often work together to create a comprehensive treatment plan for patients combining different types of treatments.
There are two kinds of surgeries:
Pleurectomy decortication involves the removal of the pleura.
Extrapleural pneumonectomy involves the eradication of the pleura, lungs, pericardium, and part of the diaphragm. The pericardium and the diaphragm are subsequently reconstructed with special material. The hospitalization time is between 14 and 21 days. It takes longer in case of complications.
With respect to chemotherapy, a combination of cisplatin and pemetrexed is the most commonly used anticancer treatment.
With regard to radiation therapy, doctors use radiation to annihilate the cancer cells. They use them for the treatment of mesothelioma.
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The accuracy of the content has been reviewed by the Medical Commission of Turquie Santé.
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