Hodgkin’s disease is a kind of cancer that has an impact on the lymphatic system. There is an unusual increase in a certain kind of white blood cell (lymphocytes). It is represented by the appearance of particular abnormal cells (Sternberg cells). This is the difference between Hodgkin’s lymphoma and all other lymphomas that are called “non-Hodgkin’s lymphomas”.
In the case of Hodgkin’s lymphoma, the proliferation of abnormal cells leads to increased lymph node's volume. Lymphocytes are no longer functioning properly. As a result, the body loses part of its defence system against viruses and bacteria and, as a result, infections occur more easily.
It is likely that the disease initially appears in one place, usually a lymph node, sometimes elsewhere in the lymphatic system: in the spleen, liver, or bone marrow.
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What are the Symptoms of Hodgkin's disease?
The hyperactive immune system due to autoimmune disorders may cause the overgrowth of lymphocytes and their abnormal multiplication. This can increase the risk of them differentiating into Hodgkin's lymphoma.
The most common symptom of Hodgkin lymphoma includes swelling of lymph nodes, which causes a lump to form under the skin in some parts of the body. This mass is usually not painful. It can be formed in one or more of the following areas:
- On the side of the neck;
- In the armpit;
- Around the groin.
Call your doctor in Istanbul Turkey right away if you have symptoms of lymphoma. They may be signs of other conditions, and it is important to get an accurate diagnosis.
Hodgkin's lymphoma & non-Hodgkin's lymphoma
The main difference between Hodgkin's lymphoma and non-Hodgkin's lymphoma is the type of lymphocyte (white cells) that is involved. Hodgkin's lymphoma is characterized by the existence of Reed-Sternberg cells that a doctor can observe using a microscope. In non-Hodgkin lymphoma, these big multinucleated cells with abundant cytoplasm are not present.
Hodgkin's lymphoma is famous for being one of the most curable cancers. However, non-Hodgkin lymphoma is more severe because it spreads faster than other types of cancer.
Cost of Hodgkin Lymphoma Treatment in Istanbul Turkey
To diagnose Hodgkin's disease, your doctor will do a physical exam and ask you questions about your medical history. Your doctor will also order certain tests so that he can make an appropriate diagnosis. The following tests can be performed:
- Imaging tests like x-rays or CT scans.
- A lymph node biopsy: This involves removing a piece of tissue from the lymph node to check for abnormal cells.
- Blood tests, such as a complete blood count (FSC),to measure the levels of red blood cells, white blood cells, and platelets.
- An Immunophenotyping test to determine the type of lymphoma cells present.
- Lung function tests to determine if your lungs are working well.
- An echocardiogram to determine if your heart is working well.
- A bone marrow biopsy: This includes removing and examining the bone marrow inside your bones to see if cancer has spread.
The cost of the diagnosis and therapy of Hodgkin's includes the fees of all the previous tests and examinations.
Advances in Hodgkin lymphoma treatment in Turkey in recent decades have dramatically increased the survival rate. According to Turquie santé, the relative survival rates of all those diagnosed with Hodgkin's disease are as follows:
- The five-year survival rate is approximately 86%.
- The 10-year survival rate is around 80%.
Here are the five-year survival rates for the different stages:
- Phase 1 is around 90 percent;
- Phase 2 is around 90 percent;
- Phase 3 is around 80 percent;
- Phase 4 is around 65 percent.
These rates may vary depending on the stage of the disease and the age of the individual.
How is Hodgkin Lymphoma treated?
The doctor will identify the stage of the disease to specify an adequate cure. The major therapy choices are chemotherapy and radiotherapy.
Radiation therapy uses high-energy beams of radiation to ruin cancer cells. Chemotherapy involves the use of drugs that can kill cancer cells. Chemotherapy drugs can be given by mouth or injected into a vein, depending on the drug.
Immunotherapy or stem cell transplant can also be used if you do not respond to chemotherapy or radiotherapy. A stem cell transplant involves injecting healthy cells called stem cells into your body to replace cancer cells in your bone marrow.
Hodgkin Lymphoma treatment in Istanbul Turkey: Best Clinics & Prices
We choose our partner doctors, clinics, and hospitals in Istanbul, Ankara, Antalya, and Izmir in Turkey, based on annual qualification reports. The main selection criterion for Turquie santé is the number of operations or procedures performed. It integrates experience, quality certificates, and reputation in a given field.
Our advisers will put all their knowledge at your disposal to help you choose the best clinics and hospitals. You can request a free quote to have more details about the cost and the price of Hodgkin lymphoma treatment in Istanbul Turkey.
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Around 85% of people diagnosed with Hodgkin's lymphoma have a life expectancy of at least five years.
Lymphatic system cancer can affect people of any age, but it is more common in young adults and people aged 15 to 40, as well as in people over 55. However, it's important to note that Hodgkin's disease can occur in both children and older people.
Hodgkin's disease is generally considered to be sporadic, meaning that it is not directly inherited from parents. The most significant relational link in terms of family history and Hodgkin's lymphoma concerns a twin affected with the disease.
Thus, the vast majority of lymphoma cases occur at random and are not related to specific genetic factors. According to the ACS (American Cancer Society),only 5% of Hodgkin's disease cases are genetically linked.
The treatment duration of Hodgkin's disease can vary depending on several factors, including:
- The stage of the disease
- The individual patient characteristics
- The specific treatment protocol that was chosen by the medical team (chemotherapy, stem cell transplant, radiotherapy, etc.).
In general, treatment of Hodgkin's disease can last several months.
According to general statistics, the 5-year survival rate for Hodgkin's disease is around 86% to 90% for patients with early stages (stages 1-2) and around 80% for patients with advanced stages (stages 3-4). It should be noted that these figures are general estimates and may vary according to various individual factors.