Hodgkin's disease, also known as Hodgkin's lymphoma, is a form of cancer that primarily affects the lymphatic system, an essential component of the immune system. Named after the English physician Thomas Hodgkin, the disease is relatively rare, accounting for around 0.5% of all cancers diagnosed each year.
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What is Hodgkin's Disease?
Hodgkin's disease is characterized by the presence of abnormal cells, called Reed-Sternberg cells, in the lymph nodes. In people with Hodgkin's disease, these large malignant cells cause the lymph nodes to enlarge, usually in the neck, armpit, or groin. As the disease progresses, it becomes harder for your body to fight off infections, and this leads to cancer of the lymphatic system.
Hodgkin's lymphoma can appear at any age, but most often affects young adults between the ages of 15 and 35, as well as people over 55. For children affected by this disease, over 90% of cases have a good cure rate thanks to the treatment administered. It is important to note that a virus known as Epstein-Barr virus (EBV) is considered one of the risk factors for Hodgkin's disease. Indeed, in some cases of this lymphoma lump, the microbe is found in cancer cells.
What are the Symptoms of lymph system cancer?
The characteristic symptom of Hodgkin's disease is swollen lymph nodes, causing a mass to form under the skin (lymphoma lump). The lump is not usually painful. However, other symptoms may also accompany the presence of lymphoma. In fact, these signs can vary from person to person, but some are common and can alert individuals and our healthcare professionals in Turkey, such as :
- Itchy skin
- Unexplained weight loss
- Profuse night sweats
You can contact the Turquie Santé team if you experience any of these symptoms. In fact, our team puts at your disposal the best clinics and surgeons in Istanbul, Turkey to ensure your care under the best conditions and at the best price.
Hodgkin's & non-Hodgkin's lymphoma
The main difference between Hodgkin's lymphoma and non-Hodgkin's lymphoma (NHL) is the type of lymphocyte (white cells) that is involved. Hodgkin's lymphoma is characterized by the existence of Reed-Sternberg cells that a doctor can observe using a microscope. In non-Hodgkin lymphoma (NHL), these big multinucleated cells with abundant cytoplasm are not present.
Hodgkin's lymphoma is famous for being one of the most curable cancers. However, non-Hodgkin lymphoma (NHL) is more severe because it spreads faster than other types of cancer.
Lymphoma lump diagnosis and cost at our partner clinics in Istanbul, Turkey
The doctor may perform a physical examination to check for swollen lymph nodes and other symptoms associated with Hodgkin's disease. He will also ask you questions about your medical history. Blood tests to assess the presence of specific markers are often necessary to confirm the diagnosis. You may also be asked to perform certain tests so that the specialist can make an appropriate diagnosis, such as :
- Imaging tests such as X-rays or CT scans
- Lymph node biopsy: a piece of lymph node tissue is removed to check for the presence of abnormal cells (Reed-Sternberg cells)
- Immunophenotyping to determine the type and form of Hodgkin's lymphoma present
- Pulmonary and cardiac function tests
- Bone marrow biopsy: this involves removing and examining the bone marrow to see if the lymphatic system cancer has spread in the body
The cost of the diagnosis and therapy of the lymphoma lump includes the fees of all the previous tests and examinations.
Lymphoma lump prognoses
Advances in the treatment of Hodgkin's lymphoma over recent decades have considerably increased survival rates. According to Turquie Santé, the average survival rate for people diagnosed with Hodgkin's disease is around 86% over five years. The percentages differ according to the stage at which the disease was detected. They range from 90% in the case of detection in Phase 1 to 65% if the disease was detected in Phase 4. It should be noted that these rates may also vary according to the individual age.
Disease treatment in Istanbul, Turkey
Once diagnosed, Hodgkin's disease is classified into different stages, depending on the extent to which the cancer has spread throughout the body. Treatment depends on the stage of the disease, the patient's age, and other individual factors. Common treatment options at our partner clinics in Turkey include chemotherapy, radiotherapy, targeted therapy, and, in some cases, stem cell transplantation. The various types of therapy are offered at our clinics at the lowest possible cost.
Radiotherapy uses high-energy beams of radiation to destroy cancer cells. Chemotherapy, on the other hand, involves the use of drugs that can kill cancer cells. As, the drugs used may be administered orally or injected into a vein, depending on the type of treatment. Immunotherapy or stem cell transplantation may also be used if you don't respond to chemotherapy or radiotherapy. This type of treatment consists of injecting healthy cells into your body to replace the cancer cells.
Lymph Cancer Treatment in Istanbul, Turkey: Best Clinics & Prices
We choose our partner doctors, clinics, and hospitals in Istanbul, Ankara, Antalya, and Izmir in Turkey, based on annual qualification reports. The main selection criteria for Turquie Santé are the quality and the number of operations or procedures performed by the health establishment. It integrates experience, quality certificates, and reputation in a given field.
Our advisers will put all their knowledge at your disposal to help you choose the best clinics and hospitals. You can request a free quote to have more details about the cost and the price of Hodgkin lymphoma treatment in Istanbul, Turkey.
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Around 85% of people diagnosed with Hodgkin's lymphoma have a life expectancy of at least five years.
Lymphatic system cancer can affect people of any age, but it is more common in young adults and people aged 15 to 40, as well as in people over 55. However, it's important to note that Hodgkin's disease can occur in both children and older people.
Hodgkin's disease is generally considered to be sporadic, meaning that it is not directly inherited from parents. The most significant relational link in terms of family history and Hodgkin's lymphoma concerns a twin affected with the disease.
Thus, the vast majority of lymphoma cases occur at random and are not related to specific genetic factors. According to the ACS (American Cancer Society),only 5% of Hodgkin's disease cases are genetically linked.
The treatment duration of Hodgkin's disease can vary depending on several factors, including:
- The stage of the disease
- The individual patient characteristics
- The specific treatment protocol that was chosen by the medical team (chemotherapy, stem cell transplant, radiotherapy, etc.).
In general, treatment of Hodgkin's disease can last several months.
According to general statistics, the 5-year survival rate for Hodgkin's disease is around 86% to 90% for patients with early stages (stages 1-2) and around 80% for patients with advanced stages (stages 3-4). It should be noted that these figures are general estimates and may vary according to various individual factors.