What is liver transplantation?
This is a very delicate operation to take a liver or a part of that of a living donor or brain dead, to transplant into a receiver while ensuring its good functionality.
Who is this procedure for?
- People with liver damage caused by chronic viral hepatitis
- People with non-alcoholic fatty liver disease or primary biliary cirrhosis
- People in need of tumor removal
- Rejection of the liver
- Vascular and biliary complications
- Complications related to anesthesia
Intervention or treatment's duration
- Between 5 and 8 hours
- A month of rest for the patient and the donor
- Total recovery after 6 months
What are the indications for liver transplantation?
Liver transplantation indications are asked by the doctor:
Chronic cholestatic diseases of the liver: namely, primary biliary cirrhosis, sclerosing cholangitis and biliary atresia.
- Hepatic parenchymal diseases: cirrhosis post hepatitis or autoimmune cirrhosis or alcoholic cirrhosis.
- Fulminant hepatitis and fulminant sub
- Primary cancer of the liver
A genetic metabolic disease (Wilson's disease, alpha-1-antitrypsin deficiency, hemochromatosis ...
What are the contraindications?
In some situations, liver transplantation can not be performed:
- In case of visceral failure: heart failure, respiratory failure ...
- An uncontrolled general infection
- Presence of neoplasia
- HIV infection ...
How is the intervention done in Turkey ?
The patient must be well prepared for the kidney transplant. A preoperative assessment is requested by the surgeon. A general pre-anesthesia consultation is mandatory.
The donor and the recipient must have the same blood group. An immunological assessment of the donor and the recipient is requested. Several additional examinations must be carried out between a blood and radiological report. The cross match between the receiver and the donor must be negative (this is the rejection test). To prevent rejection, two to three immunosuppressants are associated. Corticosteroids, azathioprine, ciclosporins and mycophenolate are indicated, three of them are selected.
The transplant is performed in an operating room while respecting the rules of strict aseptic to prevent any risk of infection.
What are the main complications?
- An immediate rejection
- The primary non functioning of the graft
- Vascular complications: arterial thromboses
- Biliary complications (fistulas or stenosis or ischemic sclerosing cholangitis ...)
- Infectious complications
- Complications related to immunosuppressive treatment: cortico-induced diabetes, high blood pressure, renal failure, cancer induced by immunosuppressive treatment.
- Complications related to anesthesia
What post-transplant follow-up?
The patient must be hospitalized in a resuscitation environment. Visits are prohibited because of the risk of infectious contamination.
It is also necessary to follow the living donor by the physical examination and some additional examinations.
Regular checks are mandatory. The gastrointestinal doctor follows his transplant patients. At each visit, he carries out a complete examination beginning with the interrogation, the physical examination and he asks for additional examinations.
Monitoring the function of the graft and the search for adverse effects related to treatment as well as the search for complications including the signs of rejection are the objectives of this follow-up.
Price of a liver transplant in Turkey
Liver transplantation is the effective treatment of chronic terminal liver disease of all etiologies. It is therefore necessary to continue the organ donation procedures.
The cost of a surgical procedure depends on several factors, you can request your personalized quote in order to benefit from the best costs.
You will find below a comparison between the prices of a liver transplant in Turkey and other countries.
France: 300,000 euros
Spain: 240,000 euros
United States of America: 260,000 euros
Turkey (Turquie santé): from 49,500 euros