Ovarian rejuvenation with PRP: Testimonials & Costs in Turkey

What is ovarian PRP?

Platelet-rich plasma (PRP) is an autologous platelet concentrate that is obtained by centrifugation of blood. It is characterized by a high concentration of growth factors. Its ability to stimulate tissue regeneration makes it the basis of many medical methods, including the treatment of female infertility.

The procedure involves the injection of ovarian PRP, which is extracted from the patient's blood cells. This therapy is totally innovative and recent, effectively used in different fields of medicine such as reproductive medicine where ovarian PRP allows to :

• Facilitate the adhesion of the embryo to the uterine lining (rejuvenation and thickening of the uterus)
• Activate the ovarian stem cells
• Ensure egg reproduction in women with premature ovarian failure or in menopause

Who is eligible for ovarian PRP?

Ovarian PRP, a promising therapeutic approach for female fertility, is intended for a specific group of patients.

To be eligible for this treatment, patients must meet the following criteria

• Good overall health: Ovarian PRP is only appropriate for women in good general health, free of chronic diseases or other major health problems.
• Menopausal or premenopausal women under 50: PRP can help delay menopause and stimulate ovarian activity in younger women facing premature menopause.
• Women over 35 with low ovarian reserve and low AMH: PRP may improve egg quality and quantity in women whose natural fertility declines with age.
• Low ovarian reserve and low AMH before age 35: PRP may be beneficial for younger women with low ovarian reserve, increasing their chances of success with artificial insemination or IVF.
• Women with premature ovarian failure (POI): Ovarian PRP can help stimulate ovarian activity and possibly restore ovulation. It increases the chances of spontaneous or assisted pregnancy.

On the other hand, ovarian PRP is contraindicated in the following cases

• Acute or untreated pelvic inflammatory disease.
• Cancer of the ovaries or other reproductive organs.
• Autoimmune or blood disorders.
• Pregnancy or lactation.

PRP ovarian rejuvenation process in Turkey

Ovarian rejuvenation with PRP in Turkey consists of 3 steps:

Preparation of PRP

After taking a blood sample from the patient through a normal venipuncture, the blood is centrifuged to obtain white blood cells and platelets in the serum.

Concentrated PRP is obtained, ready for injection into the ovaries.

PRP Injection

During the injection phase, the patient is lightly sedated for comfort. The PRP is then injected directly into the ovaries with a fine needle under ultrasound guidance.

The technique is similar to the follicular puncture used in IVF.

Follow-up and monitoring

The procedure is performed on an outpatient basis, which means the patient can go home the same day. For women undergoing ovarian stimulation, the PRP injection is incorporated into the IVF program.

After the injection, the patient continues to take her hormone medication and the ovarian follicles are monitored by ultrasound to assess their maturation.

Ovarian rejuvenation: A safe and effective approach

Turkey's ovarian rejuvenation technique uses ultrasound-guided injection for increased precision and efficacy. This approach allows the distribution of the injected solution to be monitored in real time, ensuring a targeted and optimal effect.

According to medical expertise, this treatment offers an excellent safety profile:

• Use of autologous blood: No risk of transmitting viruses such as hepatitis or HIV, since the treatment uses only the patient's own blood.
• No synthetic chemicals: The risk of allergic reactions is extremely low because no synthetic chemicals are injected.
• Proven procedure: This technique is similar to that used for egg retrieval for in vitro fertilization, confirming its reliability and safety.

Please contact us to learn more and discuss your individual fertility journey.

Results of treatment

It is important to remember that any therapeutic effect of growth factors can take 3 to 6 months to obtain optimal results. Indeed, any type of tissue transformation is not immediately apparent. First, it will be necessary to monitor ovarian improvement (production of egg cells) by analyzing blood levels of hormones such as:

• Anti-Müllerian hormone (AMH).
• Estradiol.
• Follicle Stimulating Hormone (FSH).
• Luteinizing hormone (LH).

This is done at monthly intervals, in women who do not have menstruation. It is also performed during menstrual flow in women who have been menstruating for three months. If AMH increases, while FSH, LH, and estradiol levels decrease, we are looking for objective evidence of ovarian rejuvenation. In women with ovarian failure, there may be a spontaneous return of the menstrual cycle. Even if ovarian rejuvenation is observed, pregnancy may not necessarily occur. This is because of other factors that can interfere with a natural pregnancy, such as sperm problems.